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Mirai Medical Ltd, a manufacturer of a precision cancer therapy platform , today announced the first procedures in the clinical trial to evaluate ePORE® therapy and EndoVE®, a novel breakthrough technology that can treat gastrointestinal cancers endoscopically in an outpatient setting with minimum hospitalisation for the patient. The first procedure in the VECTOR trial (NCT04649372) was performed this week at Nottingham NHS Trust, United Kingdom in a team led by Mr. Simon Parsons. The VECTOR trial aims to establish the safety and efficacy of treating patients with inoperable oesophageal cancer or gastric cancer in an outpatient setting, using an endoscopic system [...]

ATHENS, Ga. and RESEARCH TRIANGLE PARK, N.C., April 14, 2021 (GLOBE NEWSWIRE) -- Aruna Bio, Inc., a leader in the development of neural exosomes for the treatment of neurodegenerative diseases, today announced the closing of a common stock financing totalling $10.8 million. Proceeds from the raise will support the company’s business plan through mid-2022. “This capital will allow us to continue our efforts to deliver important therapeutics to the central nervous system using a novel approach to potentially treat a number of extremely debilitating neurodegenerative diseases,” stated Dr. Mark A. Sirgo, Chief Executive Officer.   Read Full Article on Globe Newswire

Serial entrepreneur Gerard Ryan, who sold his previous company to Dublin-listed Icon for €50 million, has agreed another multimillion euro sale, with US company Advarra buying his latest business Longboat Clinical. The pharmatech start-up has been acquired by Advarra for an undisclosed sum, although informed sources said it represented one of the biggest M&A deals in Ireland this year. Longboat, which has facilities in Dublin and Limerick, has developed a cloud-based platform which helps to manage clinical trials. It employs about 100 people. Mr Ryan, a Limerick pharmacist who founded Longboat in 2014, also previously established Firecrest Clinical, which was bought [...]

Deciphex, an Irish tech company that develops software to accelerate the delivery of pathology services, has raised $6.2 million (€5.4 million) to further accelerate research and development and market entry. This brings total funding to date to nearly €8 million for a company that was founded in 2017 by Dr Donal O’Shea.   Read Full Article from Irish Times

HBAN (Halo Business Angel Network), the all-island organisation responsible for the promotion of business angel investment, and a joint initiative of Enterprise Ireland and InterTradeIreland, today announces that its new London Syndicate plans to invest €3 million in Irish start-ups over the next three years.

HBAN (Halo Business Angel Network), the all-island organisation responsible for the promotion of business angel investment, and a joint initiative of Enterprise Ireland and InterTradeIreland, today announces that it was crowned Globally Networked Organisation 2018 at the EBAN (European Business Angel Network) Awards Ceremony held in Sofia, Bulgaria, on Monday 25th June.

Angels talk a lot about mentoring, but how many know what it really means? If you can’t describe what a great mentor does, you’ve probably never been one.  A great mentor relationship is actually a pretty rare and special thing.  It doesn’t come about all that often, and it’s not something that can be forced.

The European Business Angel Network (EBAN), which is the pan-European community for the early stage investors covering over 150 member organizations in more than 50 countries announced its new President today. Peter Cowley, serial entrepreneur, invested investor and UK Angel of the Year 2014-15, has been appointed by the association to take the lead of the organisation for the next two years.

CB Insights recently published a study on the most common reasons startups fail. They looked at the cause of death on 101 start-ups and, not surprisingly, "Market," "Cash" and "Team" were major factors.  But what might surprise many is that all three of those factors out-ranked "competition" as a source of death. There is an adage that start-ups don’t get killed, they commit suicide. CB Insights' study lends some credence to that idea.